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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOPEY2
All Species:
29.7
Human Site:
S1755
Identified Species:
50.26
UniProt:
Q9Y3R5
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3R5
NP_005119.2
2298
258184
S1755
V
K
G
G
D
E
K
S
P
L
V
D
I
P
V
Chimpanzee
Pan troglodytes
XP_531552
2298
258112
S1755
V
K
G
G
D
E
K
S
P
L
V
D
I
P
V
Rhesus Macaque
Macaca mulatta
XP_001084653
2286
256620
S1743
V
K
G
G
D
E
K
S
P
L
V
D
I
P
V
Dog
Lupus familis
XP_544874
2297
257913
A1754
Q
I
R
G
D
E
K
A
P
L
V
D
I
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHQ6
2295
257491
S1753
Q
I
K
G
D
E
K
S
P
L
V
D
I
P
V
Rat
Rattus norvegicus
XP_001055500
2294
257490
S1752
Q
I
K
G
D
E
K
S
P
L
V
D
I
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512569
2247
251024
S1708
Q
I
K
G
E
E
K
S
S
L
V
D
I
P
M
Chicken
Gallus gallus
XP_001232723
2283
257889
S1741
Q
I
K
G
E
E
K
S
S
L
V
D
I
P
M
Frog
Xenopus laevis
Q642P2
2270
256829
S1725
Q
I
K
G
D
E
K
S
S
L
V
D
I
P
M
Zebra Danio
Brachydanio rerio
NP_956904
817
86774
E289
S
A
P
F
T
L
Q
E
L
L
Q
G
Q
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBE8
2599
291169
S2032
I
R
V
M
P
M
D
S
F
V
M
T
L
H
H
Honey Bee
Apis mellifera
XP_395999
2434
273219
T1896
I
R
V
M
P
I
D
T
L
V
Q
T
V
H
Q
Nematode Worm
Caenorhab. elegans
Q9XW10
2417
267134
N1824
I
T
T
I
D
K
A
N
F
P
T
E
E
P
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03921
1698
194669
E1170
L
E
P
L
E
L
L
E
N
L
I
S
I
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.8
89.9
N.A.
86.4
86.4
N.A.
73.9
75.2
69
21.9
N.A.
27.6
32.1
22.3
N.A.
Protein Similarity:
100
99.7
96
94.6
N.A.
92.4
92.5
N.A.
83
85.4
82
28.7
N.A.
47
53.2
40.9
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
80
80
N.A.
60
60
66.6
6.6
N.A.
6.6
0
13.3
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
80
N.A.
73.3
73.3
73.3
13.3
N.A.
40
33.3
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
58
0
15
0
0
0
0
65
0
8
0
% D
% Glu:
0
8
0
0
22
65
0
15
0
0
0
8
8
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
15
0
0
0
0
0
0
% F
% Gly:
0
0
22
65
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
8
% H
% Ile:
22
43
0
8
0
8
0
0
0
0
8
0
72
0
0
% I
% Lys:
0
22
36
0
0
8
65
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
0
15
8
0
15
79
0
0
8
0
8
% L
% Met:
0
0
0
15
0
8
0
0
0
0
8
0
0
0
22
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
15
0
15
0
0
0
43
8
0
0
0
72
0
% P
% Gln:
43
0
0
0
0
0
8
0
0
0
15
0
8
0
8
% Q
% Arg:
0
15
8
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
0
0
0
0
0
0
65
22
0
0
8
0
0
15
% S
% Thr:
0
8
8
0
8
0
0
8
0
0
8
15
0
0
0
% T
% Val:
22
0
15
0
0
0
0
0
0
15
65
0
8
0
43
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _